The thermo-mechanical behaviour of sandwich panels with lattice core structures is investigated, comparing the real cellular solid structures’ response with an equivalent homogenised model [1]. Different Body Centred Cubic cell configurations have been considered, and depending on the configuration, the homogenised materials showed isotropic or orthotropic properties [2]. Metal composite core lattice structure and ceramic materials with variable stiffness distribution have been considered. Different parametric studies have been conducted varying the strut’s diameter, the strut’s waviness and the thickness ratio of the composite struts. Thermo-mechanical analyses have been carried on and results reveal insights into the effects of core structure parameters on the mechanical response of sandwich panels, aiding in design optimisation and structural enhancement [3]. Thermal evolution along the structural thickness is investigated in order to improve the detection of structural discontinuities, e.g defects, crack, delamination, etc.. This study is part of a UK Space Agency funded project aimed to investigate the use of a bonding technique namely Transient Liquid Phase Diffusion Bonding to manufacture suitable sandwiched structures for Space Application. Possible design solutions are given depending on the application requirements and the structural boundaries. REFERENCES [1] O.C. Zienkiewicz and R.L. Taylor, The finite element method, McGraw Hill, Vol. I., 1989, Vol. II, (1991). [2] B. Blakey-Milner et al., “Metal additive manufacturing in aerospace: A review”, Materials & Design, 209, 110008 (2021). [3] S. Valvano, “Homogenised properties of lattice metal composite cell”, Facta Universitatis, Series: Mechanical Engineering, (2024).